Black Death (Bubonic Plague) – 200MSmallpox – 56MSpanish Flu – 40-50MPlague of Justinian – 30-50MHIV/AIDS – 25-35MThe Third Plague – 12MCOVID-19 – 6.6MAntonine Plague – 5M17th Century Great Plagues – 3MAsian Flu – 1.1M